In Memoriam – John Mannick, MD

Dr. Mannick served as Moseley Professor of Surgery at Harvard Medical School between 1976-1994. He was a national and international leader in vascular surgery, surgical research and a dedicated educator who provided seminal contributions in transplantation immunology and in understanding the role of the intrinsic immune system in burns and other forms of acute injury.

Dr. Mannick contributed many successful techniques to the practice of vascular surgery. This includes vein grafts to reconstruct the tibial and peroneal arteries, the reduction of mortality from abdominal aortic aneurysm repair from more than five percent to less than two percent through the use of volume loading and minimal dissection of the aorta and iliac arteries. In addition, the use of axillo-femoral and femoro-femoral grafts to correct aortoiliac occlusive disease in certain high risk patients, and the demonstration that autogenous tissue reconstruction techniques can be applied with very high rates of long term success in over ninety percent of patients with limb-threatening femoropopliteal and infrapopliteal occlusive disease.

Also a skilled administrator, Dr. Mannick made a major contribution to the growth of the Department of Surgery at the Brigham and the services it could offer during the planning and formation of the new Brigham and Women’s Hospital which opened in 1980.

Click here to view Dr. Mannick’s obituary.

Welcoming New Faculty – Shailesh Agarwal, MD

Please join us in welcoming Shailesh Agarwal, MD, as a new faculty member in the Department of Surgery.

Shailesh Agarwal, MD
Associate Surgeon, Division of Plastic and Reconstructive Surgery

Dr. Agarwal received his undergraduate degree from the University of Michigan and received his medical degree from the University of Chicago Pritzker School of Medicine. He then completed his residency training in Plastic Surgery and an NIH-funded post-doctoral research fellowship at the University of Michigan. He subsequently completed a fellowship in microsurgical reconstruction at the University of Chicago.

Dr. Agarwal’s clinical interests include reconstruction of the breast, lymphatic system, chest wall, trunk/lower extremity, and head/neck, as well as gender surgery. Dr. Agarwal’s laboratory research is centered on genetic and epigenetic re-programming to modify cell function for tissue regeneration.

Matthew J. Carty, MD, Awarded $2.9M Department of Defense Grant

Matthew J. Carty, MD, has been awarded a $2.9M Department of Defense grant for his study, “A Novel Approach to Lower Extremity Residual Limb Revision to Augment Volitional Motor Control, Restore Proprioception, and Reverse Limb Atrophy.”

The objective of the study is to modify the residual limbs of patients who have already undergone lower extremity amputations so as to include biological actuators that will enable the successful employment of next generation lower extremity prostheses, diminish/eliminate phantom limb pain, restore proprioception and regenerate lost muscle mass.

Matthew J. Carty, MD Headshot

Matthew J. Carty, MD
Associate Surgeon, Division of Plastic and Reconstructive Surgery, Brigham and Women’s Hospital
Director,  Lower Extremity Transplant Program, Brigham and Women’s Hospital
Associate Professor of Surgery, Harvard Medical School

Matthew J. Carty, MD, is an associate surgeon in the Division of Plastic and Reconstructive Surgery at Brigham and Women’s Hospital (BWH), an associate professor of surgery at Harvard Medical School and a research scientist at the MIT Media Lab Center for Extreme Bionics.

Dr. Carty’s clinical expertise is in complex reconstruction of the extremities and trunk, for which he serves as the director of the BWH Lower Extremity Transplant Program and the co-director of the BWH Microsurgical Breast Reconstruction Program.

His primary research interests involve surgical approaches to maximize limb function in the setting of severe traumatic injury, including novel procedures related to limb amputation, limb salvage and bioprosthetic neural linkage systems.